Consideraciones juridicas entorno al consentimiento en la Ley 19.451.

47 h. ; 28 cm.Este trabajo aborda algunos elementos de la ley 19.451 sobre trasplantes de órganos. El primer capítulo desarrolla algunas generalidades en torno a la ley 19.451 y a los trasplantes de órganos. El segundo capítulo aborda la problemática de la muerte cerebral tanto en sus aspectos generales, como en el derecho español y chileno. El tercer capítulo desarrolla la problemática de la validez del consentimiento de donar según la ley 19.451. Finalmente, el cuarto capítulo desarrolla algunos elementos básicos de la llamada “socialización del cadáver”

Principales problemas que se presentan en un estudio de titulo de dominio

83 p.Esta investigación pretende identificar las situaciones problemáticas que se presentan con mayor frecuencia al realizar un estudio de títulos de dominio. El objetivo de ello es poder contar con un documento que contenga una descripción general de cada problema, señale sus variantes y además entregue posibles soluciones a las principales inquietudes emanados de los mismos. Para lograr el objetivo propuesto, se revisaron las principales obras escritas en Chile referentes a este tema, pero fundamentalmente se consultó la opinión, de las personas que por su actividad profesional están íntimamente ligadas a la materia como son, los Abogados, Notarios y Conservadores de Bienes Raíces

Capacidad de ejercicio de las personas naturales en la actuacion ante notario

60 p.Esta investigación pretende identificar los problemas que debe enfrentar el Notario en los casos en que le corresponda certificar la capacidad de ejercicio de las personas físicas. Además, de lo antes señalado, se buscará determinar si la ley le ha encomendado expresamente al Notario el cumplimiento de la función ya descrita, o si bien, esto obedecería más bien a una suerte de deber funcionario. También podremos apreciar, en el desarrollo del presente trabajo, la utilidad o beneficios que puede reportar la interrelación del derecho con otras disciplinas Con el fin de alcanzar los objetivos propuestos, se realizó un estudio y análisis de la bibliografía pertinente. Pero además, dada las características de la hipótesis planteada, se consultó la opinión de las personas que deben enfrentar esta problemática, es decir, los Notarios

Fator de inibição da migração de macrófagos MIF -794 CATT5-8 e suscetibilidade à tuberculose

Introdução: O estabelecimento de determinantes genéticos associados ao desenvolvimento da TB é um desafio, considerando as frequências divergentes entre as diferentes populações. O objetivo deste estudo foi avaliar, em um estudo caso-controle, a associação entre o polimorfismo MIF -794 CATT5-8 e a susceptibilidade à TB pulmonar em uma população do sul do Brasil. Métodos: Estudo caso-controle. Foram incluídos pacientes com idade> 18 anos com diagnóstico de TB pulmonar. O grupo controle foi composto por doadores de sangue, contactantes domiciliares, não aparentados, saudáveis e com idade> 18 anos. Foram genotipadas as variações do MIF -794 CATT5-8 usando sequenciamento de PCR e eletroforese capilar. Resultados: 126 pacientes e 119 controles foram incluídos. O genótipo 5/5 foi mais frequente entre os casos (15,1%) do que nos controles (5,9%) (p = 0,019). Os casos apresentaram maior frequência do alelo 5 (29,4%) em relação aos controles (19,3%) (p = 0,010). Comparando os pacientes com genótipos 7 / X + 8 / X com aqueles com outros genótipos, não houve diferença estatisticamente significativa (p = 0,821). Não houve diferença estatisticamente significativa comparando os pacientes com alelos 7 e 8 com aqueles com alelos 5 e 6 (p = 0,608). Conclusões: No presente estudo, encontramos que o genótipo 5/5 e o alelo 5 de MIF -794 CATT5-8 foram mais frequentes em pacientes com TB do que em controles. Mais estudos, incluindo a quantificação dos níveis de MIF, são necessários para melhor avaliar a associação entre o polimorfismo MIF -794 CATT5-8 e a susceptibilidade à TB pulmonar.Introduction: The establishment of candidate genetic determinants associated with TB development is a challenge, considering the divergent frequencies among different populations. The objective of this study was to evaluate, in a case-control study, the association between MIF -794 CATT5-8 polymorphism and susceptibility to pulmonary TB in a population of southern Brazil. Methods: Case-control study. Patients > 18 years old, diagnosed with pulmonary TB were included. The control group consisted of blood donors and household contacts, not relatives, healthy and > 18 years old. MIF -794 CATT5-8 were genotyped using sequencing of PCR and capillary electrophoresis. Results: 126 patients and 119 controls were included. The genotype 5/5 was more frequent among cases (15.1%) than in controls (5.9%) (p=0.019). Cases had more frequently the allele 5 (29.4%) as compared with controls (19.3%) (p=0.010). Comparing patients with 7/X + 8/X genotypes with those with other genotypes, there was no statistically significant difference (p = 0.821). There was no statistically significant difference comparing the patients with alleles 7 and 8 with those with alleles 5 and 6 (p = 0.608). Conclusions: In the present study, we found that the genotype 5/5 and the allele 5 of MIF -794 CATT5-8 were more frequent among TB patients than in controls. Further studies, including MIF levels quantification are necessary to better evaluate the association between MIF -794 CATT5-8 polymorphism and susceptibility to pulmonary TB

Association of occult chronic kidney disease with cardiovascular risk and their risk factors in university workers

Occult chronic kidney disease (OCKD) and cardiovascular risk (CVR) share risk factors that trigger chronic degenerative diseases. Aim. To assess the association of OCKD with CVR and its risk factors in a sample of university workers. Material and methods. This is a crosssectional study. From 89 volunteers the lipid profile, glucose, urea, creatinine and uric acid were obtained from blood as well as anthropometric measures and blood pressure. They were classified by their CVR calculated by the Framingham equation, into the groups: with-CVR and without-CVR; and by their glomerular filtration rate (GFR) into: with-OCKD and without-OCKD. Then into subgroups of each CVR factor (CVRF): sex, smoking, diabetes mellitus (DM) and hypertension. The statistical differences between groups (p <0.05) and the correlation between CVR and GFR and the odds ratio (OR) for each CVRF were determined. Results. A negative correlation between the OCKD and the CVR was obtained for men (p = - 0.743, p = 0.000) and women (p = - 0.874, p = 0.000). The overall prevalence of hypertension was 23.6% (OR = 15.43 for CVR, 95% CI, 4.04 - 58.95, OR = 14.75 for OCKD, 95% CI 2.76 - 78.23) and older than 50 years of 33.7% (OR for CVR = 20.37, 95% CI, 6.25 - 66.43). Conclusions. OCKD is strongly associated with the CVR. Furthermore, each CVRF impacts in different range and level to the development of cardiovascular disease and kidney failure

Growth rings and age in Vella pseudocytisus pseudocytisussubsp. subsp. paui paui(Brassicaceae Brassicaceae)

Age characterises the population structure and determines its dynamics. The most accurate age estimation of woody plants can be obtained through dendrochronological techniques when the rings are well marked and constitute a reliable record of each annual growing season. Our work has focused on Vella pseudocytisus subsp. paui Gómez Campo, an endemic shrub which grows in a continental semiarid climate in the center of the Iberian Peninsula (Community of Aragón) (Figure 1), with only two extant populations and recently enlisted as Endangered in the Spanish Red Data List (Moreno, 2008). The objjective of this work is to supppport with dendrochronologgical data the demog p graphic monitoring carried out over the last ten years (Domínguez et al., in press), in order to assess the study of its demographic performance (vital rates, population dynamics, survival trends). Due to the fact that the species is strictly protected under the Aragonian law, we were able only to collect individuals known to be dead or removed by agricultural practices from both populations over the last ten years. After checking the existence of defined boundaries between rings, we have measured them in 126 trunk sections corresponding to 61 individuals (see Table 1

Association of occult chronic kidney disease with cardiovascular risk and their risk factors in university workers

Occult chronic kidney disease (OCKD) and cardiovascular risk (CVR) share risk factors that trigger chronic degenerative diseases. Aim. To assess the association of OCKD with CVR and its risk factors in a sample of university workers. Material and methods. This is a crosssectional study. From 89 volunteers the lipid profile, glucose, urea, creatinine and uric acid were obtained from blood as well as anthropometric measures and blood pressure. They were classified by their CVR calculated by the Framingham equation, into the groups: with-CVR and without-CVR; and by their glomerular filtration rate (GFR) into: with-OCKD and without-OCKD. Then into subgroups of each CVR factor (CVRF): sex, smoking, diabetes mellitus (DM) and hypertension. The statistical differences between groups (p &lt;0.05) and the correlation between CVR and GFR and the odds ratio (OR) for each CVRF were determined. Results. A negative correlation between the OCKD and the CVR was obtained for men (&rho; = - 0.743, p = 0.000) and women (&rho; = - 0.874, p = 0.000). The overall prevalence of hypertension was 23.6% (OR = 15.43 for CVR, 95% CI, 4.04 - 58.95, OR = 14.75 for OCKD, 95% CI 2.76 - 78.23) and older than 50 years of 33.7% (OR for CVR = 20.37, 95% CI, 6.25 - 66.43). Conclusions. OCKD is strongly associated with the CVR. Furthermore, each CVRF impacts in different range and level to the development of cardiovascular disease and kidney failure